Repetitive Transcranial Magnetic Stimulation to Promote Regeneration in Persons With SCI

Technology
Arm/hand function
Online since 28 August 2023, updated 175 days ago

About this trial

This trial is enrolling individuals with recent (less than eight weeks) cervical spinal cord injuries to test the effect of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) on arm and hand function. TMS a is non-invasive technique which uses a magnetic field to stimulate the brain. An electrical coil (held over the head) delivers magnetic stimulation that activates a selected part of the brain; in this case, it will be directed at the part that controls movements of the affected limb. If included, participants will undergo 15 training sessions with 30 minutes of HF-rTMS, followed by 30 minutes of arm and hand training without HF-rTMS, 3-5 times per week. Final testing will be performed after 7-8 months.

Included participants

Gender
All
Age
18 - 55 years
Injury level
C2 - C6
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    All
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C2-C6
    Additionally, participants must
    NOT have metal in the skull
    NOT have a pacemaker
    NOT have a history or seizures or brain injury

    What’s involved

    Type

    Technology

    Details

    Participants will undergo 15 training sessions , 3-5 times per week consisting of: - approximately 30 minutes of HF-rTMS - 30 minutes of arm and hand training without HF-rTMS Final testing, including the assessment of arm/hand function, spasticity, pain, ability to perform everyday tasks, and overall motor and sensory function, will be performed after 7-8 months (6 months post treatment).

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 20 Aug 2022
    • Organisation
    • Kessler Foundation
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 20 Aug 2022
    • Organisation
    • Kessler Foundation

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more