Epidural Stimulation and Resistance Training After SCI

About this trial

This is a trial enrolling individuals with spinal cord injuries to test the effect of resistance training combined with spinal cord stimulation on walking function. Spinal cord stimulation is a technique for stimulating the spinal cord to modify spinal cord function. In this trial, electrodes are surgically implanted next to the spinal cord. The training program includes walking exercises in a powered wearable robotic device (exoskeleton). The study targets the additional effects of lower limb resistance training on exoskeleton-assisted walking with spinal cord stimulation. If included, individuals will randomly be assigned to one of two study groups: a) either performing the study program of exoskeleton-assisted walking with spinal cord stimulation added after 6 months; or b) performing the study program of exoskeleton-assisted walking with spinal cord stimulation along with additional resistance training of the lower extremities. Final testing will be performed after 12 months.