Transcutaneous and Epidural Stimulation in SCI

Technology

Standing/walking/mobility

Online since 5 November 2021, updated 1201 days ago

About this trial

This is a study to test the effect of two different stimulation techniques for activating spinal cord motor function in individuals with chronic motor-complete spinal cord injuries. The stimulation will be performed either with a surgically implanted electrode array placed next to the spinal cord (epidural electrical stimulation: EES) or by way of skin-surface stimulation (transcutaneous electrical spinal stimulation: TESS). Participants will undergo physical rehabilitation in combination with TESS for the first month and then will receive ESS for the final 6 months of training.

Included participants

Gender

All

Age

≥ 22 years

Injury level

C7 - T10

Severity (AIS)?

AIS-A

AIS-B

Time since injury

≥ 1 year

Injury type

Traumatic

Healthy volunteers

C7-T10

Additionally, participants must

NOT use ventilator

weigh less than 113kg (250 lbs.)

NOT have history of severe autonomic dysreflexia or hypotension

What’s involved

Type

Technology

Details

The participant will undergo physical rehabilitation in combination with TESS for the first month and then ESS for the last 6 months of training.

Potential benefits

Main benefits

Standing/walking/mobility

Additional benefits

Bladder health/function

Bone health

Bowel health

General health

Sensory function

Sexual health

Spasticity

Mechanism of action

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

Wings for Life supports SCITrialsFinder

Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

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