Transcutaneous and Epidural Stimulation in SCI

Technology
Standing/walking/mobility
Online since 5 November 2021, updated 843 days ago

About this trial

This is a study to test the effect of two different stimulation techniques for activating spinal cord motor function in individuals with chronic motor-complete spinal cord injuries. The stimulation will be performed either with a surgically implanted electrode array placed next to the spinal cord (epidural electrical stimulation: EES) or by way of skin-surface stimulation (transcutaneous electrical spinal stimulation: TESS). Participants will undergo physical rehabilitation in combination with TESS for the first month and then will receive ESS for the final 6 months of training.

Included participants

Gender
All
Age
≥ 22 years
Injury level
C7 - T10
  • Severity (AIS)?
  • AIS-A
    AIS-B
    Time since injury
    ≥ 1 year
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C7-T10
    Additionally, participants must
    NOT use ventilator
    weigh less than 113kg (250 lbs.)
    NOT have history of severe autonomic dysreflexia or hypotension

    What’s involved

    Type

    Technology

    Details

    The participant will undergo physical rehabilitation in combination with TESS for the first month and then ESS for the last 6 months of training.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    Bladder health

    Bone health

    Bowel health

    General health

    Sensory function

    Sexual health

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 16 Dec 2022
    • Organisation
    • Mayo Clinic
    • Trial recruitment status
    • Ended
    • Trial start date
    • 16 Dec 2022
    • Organisation
    • Mayo Clinic

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more