Brain Activity in People With Chronic Neuropathic Pain and Spinal Cord Injury

Technology

Pain

Online since 9 April 2024, updated 292 days ago

About this trial

This trial is enrolling 30 individuals with chronic spinal cord injury to test the effect of brain activity on neuropathic pain. If included, participants will undergo 3 separate fMRI sessions to measure brain activity. They will be shown information on this activity while trying different thinking strategies (e.g. shifting attention, imagery, mantra meditation, etc.) to change their pain experience. The study will take place over 2 days , about 1 hour on the first day and up to 7.5 hours on the second day. Final testing will occur after the second day.

Included participants

Gender

All

Age

≥ 18 years

Injury level

C4 - S5

Severity (AIS)?

AIS-A

AIS-B

AIS-C

AIS-D

Time since injury

≥ 1 year

Injury type

Traumatic

Healthy volunteers

C4-S5

Additionally, participants must

be right handed

have constant neuropathic pain

NOT have non-MRI compatible material in the body

What’s involved

Type

Technology

Details

- Participants will receive information on brain activity in pain-related regions of the brain while trying different thinking strategies to change their experience of pain. - Final testing will be performed after one day.

Potential benefits

Main benefits

Pain

Additional benefits

General health

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

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Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

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