Influence of Transcutaneous Spinal Stimulation Intensity on Spasticity After SCI

Technology
Spasticity
Online since 17 October 2023, updated 247 days ago

About this trial

This trial is enrolling 46 individuals with recent spinal cord injuries (3 months or longer) to test the effect of transcutaneous (skin surface) spinal stimulation (TSS) on spasticity. TSS is a technique for stimulating the spinal cord via surface electrodes to modify spinal cord function. If included, participants will receive three sessions of TSS at different intensities for 30 minutes (each 48 hours apart). Investigators will measure the response to the different stimulation intensities on muscle tone and spasticity before and after each intervention session through study completion, an average of two weeks.

Included participants

Gender
All
Age
≥ 16 years
Injury level
C1 - T12
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≥ 3 months
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C1-T12
    Additionally, participants must
    HAVE at least mild spasticity affecting the legs
    NOT have progressive spinal lesions
    NOT have cardiovascular irregularities

    What’s involved

    Type

    Technology

    Details

    - 3 sessions of TSS for 30 minutes (each 48 hours apart). - Final testing of muscle tone and spasticity will be performed after 2 weeks.

    Potential benefits

    Main benefits

    Spasticity

    Additional benefits

    General health

    Standing/walking/mobility

    Mechanism of action

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 8 Apr 2022
    • Organisation
    • Shepherd Center, Atlanta GA
    • Trial recruitment status
    • Ended
    • Trial start date
    • 8 Apr 2022
    • Organisation
    • Shepherd Center, Atlanta GA

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more