Neuromodulation of Ankle Muscles in Persons With SCI

Technology

Standing/walking/mobility

Online since 4 November 2021, updated 1143 days ago

About this trial

This trial is recruiting individuals with incomplete spinal cord injuries to test the effect of mechanical vibration on ankle control and ankle spasticity. Participants will undergo 8 sessions with 45 seconds of whole body vibration along with non-invasive electrical stimulation on the surface of the leg during the vibration. Whole body vibration may increase voluntary muscle control and decrease uncontrollable muscle movement. Additionally, a non-invasive magnetic field over the skull surface will be applied to examine contractions of leg and ankle muscles.

Included participants

Gender

All

Age

18 - 85 years

Injury level

C1 - T11

Severity (AIS)?

AIS-C

AIS-D

Time since injury

6 months - 85 years

Injury type

Traumatic

Healthy volunteers

C1-T11

Additionally, participants must

be able to voluntary move at least one ankle.

be able to stand and take at least 4 steps with or without assistive devices.

have moderate spasticity on at lease one ankle

What’s involved

Type

Technology

Details

The participant will undergo 8 times 45 seconds of vibration and electrical stimulation of nerves in the leg during the vibration. Additionally, another non-invasive device which uses a magnetic field to stimulate the brain (via the skull surface) to examine the function of leg muscles.

Potential benefits

Main benefits

Standing/walking/mobility

Additional benefits

General health

Spasticity

Mechanism of action

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

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