Safety Stem Cells in Spinal Cord Injury

Biological/cell based

General health

Online since 4 November 2021, updated 895 days ago

About this trial

This trial is recruiting individuals with chronic spinal cord injuries to test the safety of injecting neural stem cells. The stem cells, collected and processed from each participant’s bone marrow, will be injected into the space around the spinal cord. Each participant will be examined before the injection and then monthly for 3 months. Measurements taken at 1 and 2 years after the injection will assess any functional changes in muscle, skin, autonomic control, or pain management. There is no control group for this study; each participant will receive the stem cell injection.

Included participants

Gender

All

Age

18 - 40 years

Injury level

C5 - T12

Severity (AIS)?

AIS-A

AIS-B

AIS-C

Time since injury

1 year - 5 years

Injury type

Traumatic

Healthy volunteers

C5-T12

What’s involved

Type

Biological/cell based

Details

Bone marrow stem cells from the participant will be collected and injected into the space around their spinal cord. The participant will be examined (blood and urine samples, adverse events, physical examination) every month for 3 months. A neurological examination will be performed before the injection of Neuro-Cells, after 3 months, 1 year, and 2 years.

Potential benefits

Main benefits

General health

Additional benefits

Arm/hand function

Pain

Sensory function

Standing/walking/mobility

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

Wings for Life supports SCITrialsFinder

Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

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