Standing, Stepping and Voluntary Movement Spinal Cord Epidural Stimulation
About this trial
This is a trial to test the effect of a technique for stimulating the spinal cord with an implanted electrode placed next to the spinal cord (spinal cord epidural stimulation: scES) on standing and stepping function after spinal cord injury. If included, the participant will have an invasive procedure to place the scES stimulating electrode into the spinal canal. The participant will undergo 80 sessions stand and step training without scES. Then they will undergo 80 sessions with specific scES settings while practicing standing (stand-scES), stepping (step-scES), and voluntary movements of the legs and trunk (vol-scES). All training will also be performed with assistance of a trainer overground or in a harness on a body weight support treadmill. Stepping, standing, voluntary movement, cardiovascular, respiratory, bladder, bowel, and sexual function will be tested after 1 year.
Included participants
Traumatic
What’s involved
Type
Details
Surgical implantation of scES stimulation device with epidural electrodes 80 sessions of stand and step training without scES. 80 sessions of scES while practicing standing (stand-scES), stepping (step-scES), and voluntary movements of the legs and trunk (vol-scES). All training will also be performed with assistance of a trainer overground or in a harness on a body weight support treadmill. Stepping, standing, voluntary movement, cardiovascular, respiratory, bladder, bowel, and sexual function will be tested after 1 year.
Potential benefits
Main benefits
Standing/walking/mobility
Additional benefits
Bladder health/function
Bowel health
General health
Sexual health
Mechanism of action
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Active
- Trial start date
- 2 Nov 2020
- Organisation
- University of Louisville
- Trial recruitment status
- Active
- Trial start date
- 2 Nov 2020
- Organisation
- University of Louisville
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more