Standing, Stepping and Voluntary Movement Spinal Cord Epidural Stimulation

About this trial

This is a trial to test the effect of a technique for stimulating the spinal cord with an implanted electrode placed next to the spinal cord (spinal cord epidural stimulation: scES) on standing and stepping function after spinal cord injury. If included, the participant will have an invasive procedure to place the scES stimulating electrode into the spinal canal. The participant will undergo 80 sessions stand and step training without scES. Then they will undergo 80 sessions with specific scES settings while practicing standing (stand-scES), stepping (step-scES), and voluntary movements of the legs and trunk (vol-scES). All training will also be performed with assistance of a trainer overground or in a harness on a body weight support treadmill. Stepping, standing, voluntary movement, cardiovascular, respiratory, bladder, bowel, and sexual function will be tested after 1 year.