Neuromodulation of Spinal Locomotor Circuitry to Elicit Stepping After Pediatric Spinal Cord Injury
About this trial
This is a trial to test the effect of a technique for stimulating the spinal cord via surface stimulation (i.e., transcutaneous spinal stimulation: TcStim) on stepping in children with spinal cord injury. The study consists of 3 independent parts. If included, the participant will receive one of: 1) TcStim at single or multiple spinal levels while lying down to produce muscle activity in lower limbs; 2) TcStim while stepping on a moving treadmill with a supportive harness that holds the participant upright i.e. Body-weight support (BWS) + TcStim; 3) 60 x 1-hour BWS training sessions, 5 times per week, followed by combination training of BWS + TcStim for another 60 x 1-hour sessions, 5 times per week. Combination training activities include standing, stepping, and sitting on and off the treadmill.
Included participants
Traumatic
Non-traumatic
Ischemia
What’s involved
Type
Details
TcStim at a single or multiple spinal levels; TcStim while stepping on a moving treadmill with a body-weight support (BWS) harness that holds the participant upright 60 x 1-hour training sessions, 5 times per week, followed by a combination training + TcStim for another 60 x 1-hour sessions, 5 times per week. Combination training activities include standing, stepping, and sitting on and off the treadmill.
Potential benefits
Main benefits
Standing/walking/mobility
Additional benefits
General health
Mechanism of action
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- By invitation
- Trial start date
- 12 Apr 2021
- Organisation
- University of Louisville
- Trial recruitment status
- By invitation
- Trial start date
- 12 Apr 2021
- Organisation
- University of Louisville
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more