FLO2 for Recovery After SCI
About this trial
This is a trial to test the effect of repeatedly breathing air with low oxygen content for brief periods, alternating with breathing room air with normal oxygen content (acute intermittent hypoxia: AIH) combined with training breathing muscles to determine if their combined effect on breathing function is better than that achieved with either intervention alone. If included in this trial, the participant will complete 4x5-day interventions of 1) AIH, 2) breathing muscle strength training, 3) AIH and breathing muscle strength training, and 4) inactive intervention (sham AIH breathing room air) - not intended to have a therapeutic effect - used in a controlled trial for comparison to the active intervention. The order in which the interventions will be administered will be randomly determined. The intervention periods will be followed by a 3-week period without any intervention, during which clinical tests will be performed at 1 day, 3 days, and 1 week after the intervention.
Included participants
Traumatic
Non-traumatic
Stenosis
Spondylosis
What’s involved
Type
Details
Participants will participate in 4 randomly ordered 5-day interventions of 1) AIH, 2) breathing strength training, 3) AIH and breathing muscle strength training, and 4) inactive intervention (sham AIH). The intervention periods will each be followed by a 3-week period without any intervention, during which clinical tests will be performed at 1 day, 3 days, and 1 week after the intervention.
Potential benefits
Main benefits
General health
Additional benefits
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Ended
- Trial start date
- 15 Aug 2020
- Organisation
- University of Florida
- Trial recruitment status
- Ended
- Trial start date
- 15 Aug 2020
- Organisation
- University of Florida
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more