High Intensity Exercise in Incomplete SCI

Rehabilitation
Standing/walking/mobility
Online since 4 November 2021, updated 945 days ago

About this trial

This trial is enrolling individuals with chronic incomplete spinal cord injuries to study the effect of high-intensity exercise on walking speed. Previous studies have shown that high-intensity stepping (e.g. overground walking or locomotor training on a treadmill) leads to increased walking ability when compared to low-intensity training. Improvements in walking will also be compared between participants with different degrees of nerve and muscle activity, cardiovascular (heart) function, or genetic characteristics. If selected for the trial, participants will be randomly assigned to one of two groups; 1) a high-intensity (30 sessions of walking related activities for 40 minutes with heart rate close to 80% of reserve) or 2) a low-intensity group (control group, same exercise duration but with heart rate closer to 30% to 40% of reserve).

Included participants

Gender
All
Age
18 - 75 years
Injury level
C1 - T10
  • Severity (AIS)?
  • AIS-C
    AIS-D
    Time since injury
    1 year - 75 years
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C1-T10
    Additionally, participants must
    be able to tolerate 10 minutes of standing without blood pressure problems.
    have a body weight lower than 400 lbs (= 181 kg).
    NOT be dependent on a ventilator

    What’s involved

    Type

    Rehabilitation

    Details

    Up to 30 training sessions within 2 months. 40min of walking will be done within a 1 hour session. Training sessions will involve walking on different surfaces such as overground, treadmill, and stairs.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Jul 2019
    • Organisation
    • Indiana University
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Jul 2019
    • Organisation
    • Indiana University

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more