The Effects of rTMS in Rehabilitation Following Spinal Cord Injury

Technology
Standing/walking/mobility
Online since 16 April 2024, updated 449 days ago

About this trial

This is a trial to test the effects of repetitive transcranial magnetic stimulation (rTMS) on leg movements in combination with high-intensity resistance training on motor function after chronic spinal cord injury. rTMS is a non-invasive technique that uses an external magnetic field to stimulate the brain. A coil (held over the head) delivers the magnetic stimulation that activates the brain. If included in this trial, the participant will attend 8 weeks of resistance training in combination with 1) an active rTMS intervention or 2) an inactive intervention (sham rTMS) - used as a control for comparison to the active intervention.

Included participants

Gender
All
Age
18 - 50 years
Injury level
C1 - S5
  • Severity (AIS)?
  • AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≤ 6 months
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    have a spinal cord injury for less than 6 months.
    have an incomplete SCI.
    be between the ages of 18 and 50 years.

    What’s involved

    Type

    Technology

    Details

    8 weeks of resistance training with 1) Active rTMS intervention OR 2) inactive (sham rTMS) intervention. Additional tests including standard neurological examination, walking, strength, and sensory function before and after the 8 weeks of intervention.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    General health

    Pain

    Spasticity

    Mechanism of action

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 2 Jan 2019
    • Organisation
    • Spinal Cord Injury Centre of Western Denmark
    • Trial recruitment status
    • Ended
    • Trial start date
    • 2 Jan 2019
    • Organisation
    • Spinal Cord Injury Centre of Western Denmark

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more