Combined Robotic Training and tDCS in Chronic SCI

Technology
Arm/hand function
Online since 3 November 2021, updated 927 days ago

About this trial

This trial is recruiting individuals with chronic, incomplete spinal cord injuries to test the effect on arm and hand function of combining non-invasive brain stimulation (transcranial Direct Current Stimulation; tDCS) with use of a robotic device. Researchers want to see if supplementary tDCS will cause changes to the brain area that controls the arm, and thus will add to any functional improvement derived from robot-training. Two groups of participants will receive training of the affected hand with a robotic device. One group will have tDCS applied to the brain before the training starts. The other group will receive a sham (inactive) stimulation before training. Participants will not know whether they receive tDCS or sham stimulation. Each participant will then receive robotic training 3 times per week over 6 weeks for a total of 18 sessions. Measurements of hand and arm function will occur before and after the training phase, and at a 1-month follow-up. A key measurement will include a timed functional test to determine gross manual dexterity.

Included participants

Gender
All
Age
18 - 99 years
Injury level
C1 - C8
  • Severity (AIS)?
  • AIS-B
    AIS-C
    AIS-D
    Time since injury
    6 months - 99 years
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C1-C8
    Additionally, participants must
    have some degree of motor dysfunction in the hand
    NOT have implanted device, e.g., pacemaker

    What’s involved

    Type

    Technology

    Details

    No surgery is needed. 6-week (3 sessions/week, 18 sessions total) hand robotic training with each session preceded by 20 min anodal 2mA tDCS or sham. A follow-up assessment will be performed 1 month after the end of the training session.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Unknown
    • Trial start date
    • 1 May 2017
    • Organisation
    • Burke Medical Research Institute
    • Trial recruitment status
    • Unknown
    • Trial start date
    • 1 May 2017
    • Organisation
    • Burke Medical Research Institute

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more