Restoring High Dimensional Hand Function to Persons With Chronic High Tetraplegia

Technology
Arm/hand function
Online since 3 November 2021, updated 845 days ago

About this trial

This trial is enrolling individuals with chronic cervical (neck area) spinal cord injuries who already have a recording electrode array (BrainGate) implanted in their brain. This study will investigate using the device to enable grasping movements. Brain activity will be measured when participants think about grasping. This information will be decoded to a computer connected to a functional electrical stimulation (FES) system. FES uses small electrodes implanted in the arm, shoulder, and hand to send small electrical currents to cause contraction of weakened or paralyzed muscles. The main goal is to match the precise brain signals to the actual grasping behavior performed with FES in order to promote voluntary hand movements. Participants will be asked to either control their hand in the real word, or within a computer generated experience (virtual reality) through head-mounted displays.

Included participants

Gender
All
Age
18 - 75 years
Injury level
C1 - C8
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    1 month - 75 years
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C1-C8
    Additionally, participants must
    already have a BrainGate2 array implanted, and have demonstrated the ability to use it to control a cursor on a monitor

    What’s involved

    Type

    Technology

    Details

    Training of grasping movements and comparison of performance in a real word or a virtual reality setting.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Jun 2018
    • Organisation
    • VA Office of Research and Development
    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Jun 2018
    • Organisation
    • VA Office of Research and Development

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more