Enhancing Corticospinal Activation for Improved Walking Function

Technology
Standing/walking/mobility
Online since 3 November 2021, updated 888 days ago

About this trial

This rehabilitation trial is recruiting individuals with chronic, incomplete spinal cord injuries to test whether non-invasive, painless electrical brain stimulation (transcranial direct current stimulation -tDCS)) during training.will impact walking. Researchers want to see if brain stimulation has the potential to improve communication between the brain and spinal cord, and thus improve walking. Participants will have electrodes placed on the head that stimulate the brain during 3 motor training sessions. Each will be randomly assigned to either train with the stimulation turned on or with a sham (inactive placebo) stimulation. Neither participant nor tester will know if the stimulation or the placebo is used. Assessments will include walking function, spasticity, and ankle strength.

Included participants

Gender
All
Age
18 - 65 years
Injury level
C3 - T10
  • Severity (AIS)?
  • AIS-C
    AIS-D
    Time since injury
    1 year - 65 years
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    Yes
    C3-T10

    What’s involved

    Type

    Technology

    Details

    The participant will be randomly assigned to either receive 1) the active tDCS or 2) inactive tDCS. Training sessions of 25-30 minutes per day for 3 days of walking tests 1 day before and after the training sessions.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    General health

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Mar 2017
    • Organisation
    • Shepherd Center, Atlanta GA
    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Mar 2017
    • Organisation
    • Shepherd Center, Atlanta GA

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more