Epidural Decompression Surgery Within 24 Hours After Acute Spinal Cord Injury Improves Spinal Nerve Function

Surgery
General health
Online since 3 November 2021, updated 839 days ago

About this trial

This is a trial enrolling individuals with acute spinal cord injury to test the effect of early and delayed decompression surgery to relieve pressure on the spinal cord. Following spinal cord injury, there is often pressure on the spinal cord from structures (vertebra – the bones around the spinal cord, discs, and ligaments) that may have been displaced or broken as result of trauma.  Researchers want to see whether the timing of this procedure has an effect on recovery (strength and sensation). If included, participants will be assigned to early (within 24 hours after SCI) or late (exceeding 24 hours after SCI) epidural decompression surgery. The participant will be monitored for 6 months after the surgery.

Included participants

Gender
All
Age
16 - 85 years
Injury level
C1 - L5
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≤ 3 weeks
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C1-L5

    What’s involved

    Type

    Surgery

    Details

    If included, the participant will be assigned to early (within 24 hours after SCI) or late (exceeding 24 hours after SCI) decompression surgery, “according to the patient's condition and operation time”. The participant will be monitored for 6 months after the surgery.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Sensory function

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Unknown
    • Trial start date
    • 1 Aug 2017
    • Organisation
    • Peking University People's Hospital
    • Trial recruitment status
    • Unknown
    • Trial start date
    • 1 Aug 2017
    • Organisation
    • Peking University People's Hospital

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more