Riluzole in the Treatment of Spasticity in the Traumatic Chronic Spinal Cord Injury Condition

Drug
Spasticity
Online since 8 September 2023, updated 222 days ago

About this trial

The trial is enrolling 90 individuals with chronic cervical or thoracic spinal cord injuries to test the effect of a drug, Riluzole, on spasticity. If included, participants will receive either: 1) four varying doses of Riluzole; or 2) a placebo drug. Final testing of blood samples to determine effective dosing of Riluzole will be performed after 2 months.

Included participants

Gender
All
Age
18 - 65 years
Injury level
C4 - T12
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    12 months - 65 years
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C4-T12
    Additionally, participants must
    present with spasticity

    What’s involved

    Type

    Drug

    Details

    Participants will receive either - 1) four doses of the active drug (Riluzole) or - 2) the placebo drug. - Final testing of blood samples will be performed after 2 months.

    Potential benefits

    Main benefits

    Spasticity

    Additional benefits

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 27 May 2019
    • Organisation
    • Assistance Publique Hopitaux De Marseille
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 27 May 2019
    • Organisation
    • Assistance Publique Hopitaux De Marseille

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more