Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

Drug
Arm/hand function
Online since 18 March 2024, updated 21 days ago

About this trial

This trial is enrolling 70 individuals with acute cervical spinal cord injury to test the safety and efficacy of a drug (VX-210) on upper limb function. If included, participants will receive either the drug or a placebo. Final testing of upper limb function will be performed after 6 months.

Included participants

Gender
All
Age
14 - 75 years
Injury level
C4 - C7
  • Severity (AIS)?
  • AIS-A
    AIS-B
    Time since injury
    ≤ 72 hours
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C4-C7
    Additionally, participants must
    Not have acute SCI from gunshot or penetrating/stab wound; non-traumatic SCI (e.g., transverse myelitis, acute disc herniation); brachial plexus injury; complete spinal cord transection; or multifocal SCI

    What’s involved

    Type

    Drug

    Details

    - Participants will receive either the drug or a placebo. - Final testing of upper limb function will be performed after 6 months.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Sensory function

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Jul 2016
    • Organisation
    • Vertex Pharmaceuticals Incorporated
    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Jul 2016
    • Organisation
    • Vertex Pharmaceuticals Incorporated

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more