Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

Drug

Arm/hand function

Online since 16 April 2024, updated 92 days ago

About this trial

This trial is enrolling 70 individuals with acute cervical spinal cord injury to test the safety and efficacy of a drug (VX-210) on upper limb function. If included, participants will receive either the drug or a placebo. Final testing of upper limb function will be performed after 6 months.

Included participants

Gender

All

Age

14 - 75 years

Injury level

C4 - C7

Severity (AIS)?

AIS-A

AIS-B

Time since injury

≤ 72 hours

Injury type

Traumatic

Healthy volunteers

C4-C7

Additionally, participants must

Not have acute SCI from gunshot or penetrating/stab wound; non-traumatic SCI (e.g., transverse myelitis, acute disc herniation); brachial plexus injury; complete spinal cord transection; or multifocal SCI

What’s involved

Type

Drug

Details

- Participants will receive either the drug or a placebo. - Final testing of upper limb function will be performed after 6 months.

Potential benefits

Main benefits

Arm/hand function

Additional benefits

General health

Sensory function

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

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