Safety Study of Human Spinal Cord-derived Neural Stem Cell Transplantation for the Treatment of Chronic SCI

Biological/cell based

Standing/walking/mobility

Online since 1 November 2021, updated 898 days ago

About this trial

This study is testing the safety of stem cell transplantation in individuals with chronic cervical (neck area) spinal cord injuries. The procedure involves surgical implantation of human spinal cord-derived neuronal stem cells at the site of neurological injury in the spinal cord. Participants will receive the stem cell surgery and a follow-up of 60 months.

Included participants

Gender

All

Age

18 - 65 years

Injury level

C5 - C7

Severity (AIS)?

AIS-A

Time since injury

1 year - 2 years

Injury type

Traumatic

Non-traumatic

Healthy volunteers

C5-C7

Additionally, participants must

live within 500 miles from University of California San Diego Medical Center

NOT have penetrating injury, e.g. gunshot or knife wound

NOT have received investigational drug or device within 30 days of stem cell operation

What’s involved

Type

Biological/cell based

Details

Stem cell transplantation surgery into the spinal cord. 6 months study period and an additional 54 months follow-up.

Potential benefits

Main benefits

Standing/walking/mobility

Additional benefits

Arm/hand function

Bladder health/function

Bowel health

General health

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

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Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

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