The Canadian Multicentre CSF Monitoring and Biomarker Study
About this trial
This is a trial to study the cerebrospinal fluid (CSF) surrounding the spinal cord of individuals with acute spinal cord injuries. The trial will find out how well the spinal cord is being supplied with blood and to find molecular indicators (markers) in the CSF that may predict nervous system recovery after SCI. The study will also look at how blood pressure drugs (vasopressors) influence spinal fluid pressure. Trial participants will have a thin, temporary tube (catheter) inserted into their lower back to access spinal cord fluid 3 times per day, for 5 days. A neurological exam will follow 3, 6, and 12 months after injury.
Included participants
Traumatic
What’s involved
Type
Details
A thin tube will be inserted into the lower back for 5 days from which CSF will be taken out every 8 hours, 3 times per day. Neurological examinations after 3, 6, and 12 months after the injury. The participant will receive specific drugs against low blood pressure (NORepinephrine and/or DOPamine) after their injury and will switch between these drugs at specific time-frames.
Potential benefits
Main benefits
General health
Additional benefits
Pain
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Ended
- Trial start date
- 1 Jan 2012
- Organisation
- University of British Columbia
- Trial recruitment status
- Ended
- Trial start date
- 1 Jan 2012
- Organisation
- University of British Columbia
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more