| NCT04295538 | Safety And Efficacy Study Of Intravenous (IV) Administration Of Elezanumab To Assess Change In Upper Extremity Motor Score (UEMS) In Adult Participants With Acute Traumatic Cervical Spinal Cord Injury (SCI) | AbbVie | | - Age 18 - 70 yrs
- Level C4-C7
AIS A, B- ≤ 24 hours
| Active | 60 | PHASE2 | Drug | Arm/hand function | | | 06 September 2020 | 04 March 2020 | 62 | |
| NCT04292717 | Deficit-specific Training in Spinal Disorders | University of Zurich | | - Age 18 - 80 yrs
- Level C1-T12
AIS C, D- ≥ 6 months
- NOT have history of cardiac or pulmonary condition
- be able to walk without assistance on treadmill and 10m over ground
| Ended | 63 | NA | Rehabilitation | Standing/walking/mobility | | | 01 January 2021 | 03 March 2020 | 1 | |
| NCT04286191 | Physiological Changes Induced Through MEP Conditioning in People With SCI | Medical University of South Carolina | | - Age ≥ 18 yrs
- Level C1-S5
AIS A, B, C, D- ≥ 1 years
- be able to walk at least 10 m with or without an assistive device (except for parallel bar)
- NOT have implanted device, e.g. pacemaker
| Ended | 21 | NA | Rehabilitation | Standing/walking/mobility | | | 22 February 2021 | 26 February 2020 | 1 | |
| NCT04265560 | Progressive Resistance Training in Acute Spinal Cord Injury | Glasgow Caledonian University | | - Age ≥ 18 yrs
- Level C1-S5
AIS A, B, C, D- ≥ 2 weeks
- have partial or complete paralysis of at least two muscle groups in at least one upper limb
- be able to tolerate sitting upright in a wheelchair for at least 2 hours
- NOT be dependent on ventilator
- NOT have severe spasticity or autonomic dysreflexia
| Ended | 7 | NA | Rehabilitation | Arm/hand function | | | 01 November 2019 | 11 February 2020 | 1 | |
| NCT04250688 | Robotic Exoskeleton With Functional Electrical Stimulation in Acute Spinal Cord Injury | Shirley Ryan AbilityLab | | - Age 18 - 70 yrs
- Level C7-T11
AIS A, B, C, D- 3 days - 6 months
- NOT have an implanted device such as a pacemaker
- NOT have a medical issue that precludes full weight bearing and ambulation
- NOT weigh more than 220 lbs.
| | 10 | NA | Technology | Standing/walking/mobility | | | 01 January 2016 | 31 January 2020 | 0 | |
| NCT04241250 | Neuromodulation Techniques After SCI | VA Office of Research and Development | | - Age 18 - 70 yrs
- Level C1-T10
AIS A, B- 1 months - 70 years
- NOT have an implanted device, e.g. pacemaker
| Ended | 4 | PHASE2 | Technology | Standing/walking/mobility | | | 01 June 2020 | 27 January 2020 | 1 | |