| NCT05515419 | Allogeneic Cord Blood for Neurological Diseases in Adults | The Medical Pavilion Bahamas | | - Age ≥ 18 yrs
- Level -
AIS - ≤ 24 months
| Ended | 0 | EARLY_PHASE1 | Biological/cell based | Mental health and psychosocial factors | | 12 months | 01 July 2025 | 25 August 2022 | 0 | |
| NCT05390853 | Active tDCS Versus Sham tDCS for Upper Limb Recovery in Incomplete Tetraplegic Patients | Montecatone Rehabilitation Institute S.p.A. | | - Age 18 - 74 yrs
- Level C3-C7
AIS B, C, D- 3 months - 6 months
- NOT having any implanted devices (e.g. pacemakers, intrathecal infusers, neurostimulators, hearing aids
- NOT having any history of brain lesions
- NOT having a history of epilepsy
- NOT having a history of psychotic disorders
- NOT having a history of severe neurodegenerative disease
- NOT having a brain tumor
| Recruiting | 30 | NA | Technology | Arm/hand function | - Ashworth and Modified Ashworth Scale (MAS)
- Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Numeric Pain Rating Scale
| 10 Weeks | 24 May 2023 | 25 May 2022 | 1 | |
| NCT05302999 | Feasibility of Early Gabapentin as an Intervention for Neurorecovery | MetroHealth Medical Center | | - Age ≥ 18 yrs
- Level C1-S5
AIS A, B, C, D, E- ≥ null null
- NOT have suffered a moderate/severe traumatic brain injury (TBI)
| Recruiting | 42 | PHASE4 | Drug | General health | | 6 months | 14 March 2022 | 31 March 2022 | 1 | |
| NCT05426681 | Spinal Cord Injury Neuroprotection With Glyburide | University of Kentucky | | - Age 18 - 80 yrs
- Level C2-T12
AIS A, B, C- ≤ 8 null
| Recruiting | 12 | PHASE1 | Drug | General health | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
| One year following SCI | 07 July 2022 | 22 June 2022 | 1 | |
| NCT05429736 | Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spasticity | Shepherd Center, Atlanta GA | | - Age 18 - 70 yrs
- Level C1-T12
AIS C, D- ≥ 12 months
- be able to stand for at least 5 minutes (with or without an assistive device)
- be able to move each leg independently for at least three steps
- be able to rise from sit to stand with no more than moderate assistance from one person
| Recruiting | 28 | NA | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 2 Minute Walk Test
- Berg Balance Scale (BBS)
- Falls Efficacy Scale (FES, Tinetti)
- Spinal Cord Assessment Tool for Spastic Reflexes (SCATS)
- Spinal Cord Injury Spasticity Evaluation Tool (SCI-SET)
| 27 days | 01 March 2022 | 23 June 2022 | 1 | |
| NCT05255679 | Early FES Cycling in Acute Spinal Cord Injury for Neuromuscular Preservation and Neurorecovery | University of Alberta | | - Age 18 - 80 yrs
- Level C1-L5
AIS A, B, C, D- 14 days - 21 days
- NOT be able to walk without assistive devices
- NOT have contraindications for Transcranial Magnetic Stimulation (TMS)
- NOT have autonomic dysreflexia
- NOT have an implanted stimular or pacemaker
| Ended | 35 | NA | Rehabilitation | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L)
- Motor evoked potential
- Nerve Conduction Studies (compound motor action potentials - cMAP, sensory action potentials- SNAP, f-wave, H reflex)
- Patient Health Questionnaire-9 (PHQ-9)
- Surface Electromyography (sEMG)
| 6 months | 21 April 2021 | 24 February 2022 | 1 | |
