| NCT05601661 | Safety and Feasibility of Paired Vagus Nerve Stimulation With Rehabilitation for Improving Upper Extremity Function in People With Cervical Spinal Cord Injury | The University of Texas Health Science Center, Houston | | - Age ≥ 18 yrs
- Level C1-C8
AIS B, C, D- ≥ 12 months
- NOT have prior history of vagus nerve injury
| Ended | 6 | NA | Technology | Arm/hand function | - Capabilities of Upper Extremity Instrument (CUE- Q and CUE-T)
- Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Spinal Cord Independence Measure (SCIM)
- Toronto Rehabilitation Institute Hand Function Test
| 132 days after enrollment | 15 June 2023 | 01 November 2022 | 1 | |
| NCT05635851 | NO AD: Use of Nitric Oxide (NO) Donors for the Prevention of Autonomic Dysreflexia (AD) During Bowel Care Following SCI | Simon Fraser University | | - Age 19 - 80 yrs
- Level C1-S5
AIS - ≥ 1 years
- Have known incidence of autonomic dysreflexia.
| Recruiting soon | 26 | PHASE2 | Drug | General health | | during testing | 01 September 2025 | 02 December 2022 | 0 | |
| NCT05639946 | Brivaracetam to Reduce Neuropathic Pain in Chronic SCI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial | University of Minnesota | | - Age ≥ 18 yrs
- Level C1-S5
AIS - ≥ 3 months
- have completed inpatient rehab
| Ended | 44 | PHASE3 | Drug | Pain | - International Spinal Cord Injury Pain Classification (ISCIP)
| 3 months | 01 January 2023 | 07 December 2022 | 1 | |
| NCT05550987 | The Use of Modern Technologies in Neurorehabilitation | University of Rzeszow | Parallel Assignment | - Age 18 - 75 yrs
- Level C1-S5
AIS - All
- NOT have bone density t-score of less than -2.5
| Recruiting soon | 120 | Not Applicable | Rehabilitation | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 2 Minute Walk Test
- Barthel Index (BI)
- Berg Balance Scale (BBS)
- Box and Block Test (BBT)
- Frenchay Activities Index (FAI)
- Tardieu Scale
- Timed Up and Go Test (TUG)
- World Health Organization Disability Assessment Schedule II (WHODAS 2.0)
- World Health Organization Quality of Life- BREF (WHOQOL-BREF)
| immediately after intervention | 01 November 2022 | 22 September 2022 | 0 | |
| NCT05690074 | Epidural Stimulation in Chronic Spinal Cord Injury Patients | University Hospital, Motol | | - Age 18 - 60 yrs
- Level C7-T10
AIS A, B- ≥ 2 years
- NOT be currently ventilator dependent
| | 5 | NA | Technology | Standing/walking/mobility | - Ashworth and Modified Ashworth Scale (MAS)
- Neurogenic Bladder Symptom Score
- Neurogenic Bowel Dysfunction Score (NBD or NBDS)
- World Health Organization Quality of Life- BREF (WHOQOL-BREF)
| 12 months | 01 January 2023 | 19 January 2023 | 1 | |
| NCT05725499 | The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI) | Kessler Foundation | | - Age 18 - 75 yrs
- Level C1-T6
AIS A, B, C, D- ≥ 6 months
- NOT be ventilator dependent
- NOT have other implanted pacemaker device
| Recruiting | 5 | NA | Technology | General health | - Quality of Life Index (QLI) - SCI Version
- Surface Electromyography (sEMG)
| 6 weeks | 01 February 2023 | 13 February 2023 | 1 | |
