| NCT05301335 | Spinal COrd NeuromodulaTor by SpIneX and ScoNE to Treat NeurogeniC BladdEr - SCONE "CONTINENCE" Clinical Study | SpineX Inc. | | - Age 18 - 70 yrs
- Level C3-T8
AIS A, B, C, D- ≥ 1 years
- NO congestive heart failure
- NO other concurrent neurological disease
- NO implanted neuromodulator
- Not use indwelling urethral or suprapubic catheter for bladder management
- Not received botox injections in the bladder within the last 12 months
- Not have a symptomatic bladder infection
| Ended | 126 | NA | Technology | Bladder health/function | - Neurogenic Bladder Symptom Score
- Patient Global Improvement Index
- Urge Urinary Incontinence Episodes
| 12 weeks | 25 May 2022 | 29 March 2022 | 15 | |
| NCT05321017 | Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord Injury | Medical University of South Carolina | | - Age ≥ 18 yrs
- Level C1-C6
AIS - ≥ 6 months
- NOT have cognitive impairment
- NOT be using FES on their arms daily
- HAVE some voluntary control of wrist extensor muscles
| Recruiting | 5 | NA | Technology | Arm/hand function | - Action Research Arm Test (ARAT)
- Ashworth and Modified Ashworth Scale (MAS)
- Box and Block Test (BBT)
- Fugl-Meyer Assessment (FMA)
- Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Manual Muscle Test (MMT)
- Motor evoked potential
- Nine Hole Peg Test
| 0 | 12 October 2021 | 11 April 2022 | 1 | |
| NCT05200091 | Sensorimotor Integration Underlying Balance Control in Individuals With Incomplete Spinal Cord Injury | Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal | | - Age ≥ 18 yrs
- Level C5-T12
AIS C, D- ≥ 6 months
- be able to stand without support for 15 seconds
- NOT have cognitive deficits
- NOT have suffered moderate to severe traumatic brain injury
- NOT have a cochlear implant
| | 36 | NA | Rehabilitation | Standing/walking/mobility | - Balance Assessment: Centre of Pressure Testing
- H reflex
- Motor Evoked Potentials (MEPs)
- Nerve Conduction Studies (compound motor action potentials - cMAP, sensory action potentials- SNAP, f-wave, H reflex)
- Surface Electromyography (sEMG)
| 2 months | 09 July 2018 | 20 January 2022 | 1 | |
| NCT05218447 | Dosing of Overground Robotic Gait Training with Functional Outcomes and Neuroplasticity After Spinal Cord Injury | Baylor Research Institute | | - Age 16 - 85 yrs
- Level C1-S5
AIS C, D- ≤ 6 months
- Be currently undergoing medical care and rehabilitation at Baylor Scott & White Institute for Rehabilitation
- Must meet the Ekso Robotic frame size specification (height 5' to 6'4", weight 220lbs or less)
| Recruiting | 144 | NA | Rehabilitation | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- Fatigue Severity Scale (FSS)
- Life Satisfaction Questionnaire (LISAT-9, LISAT-11)
- Motor evoked potential
- Motor Evoked Potentials (MEPs)
- Pain Numeric Rating Scale (NRS)
- Patient Health Questionnaire-9 (PHQ-9)
- Penn Spasm Frequency Scale (PSFS)
- Spinal Cord Independence Measure (SCIM)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 9 months post spinal cord injury | 20 May 2022 | 01 February 2022 | 1 | |
| NCT05035823 | COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis | Synchron, Inc. | | - Age 21 - 75 yrs
- Level C1-C8
AIS - All
- NO history of pulmonady embolism
- NO history of deep vein thrombosis
- NO history or current psychiatric or psychological disorder
- have a study partner
| Active | 6 | NA | Technology | General health | | 12 months post implant | 27 April 2022 | 05 September 2021 | 3 | |
| NCT05265377 | Safety and Usability of the STELO Exoskeleton in People With Acquired Brain Injury and Spinal Cord Injury | MarsiBionics | | - Age 18 - 85 yrs
- Level C1-S5
AIS - All
- Have shoe size EU 36-45
- Have a height between 150-190 cm
- HAVE a spinal cord injury or aquired brain injury
| Ended | 20 | NA | Technology | General health | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Blood Pressure and Heart Rate Regulation
- Electromyography
- Pain Visual Analog Scale (VAS)
- Timed Up and Go Test (TUG)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 100 days (average time to complete the study) | 21 September 2022 | 03 March 2022 | 3 | |
