Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.
About this trial
This trial is enrolling 24 participants with chronic motor incomplete spinal cord injury to test the combination of exoskeleton-assisted walking (EAW) and transcutaneous spinal stimulation (tSS) on lower extremity function. An exoskeleton is an externally worn powered robotic device to assist movement. tSS is a non-invasive technique that uses surface electrodes to deliver electrical stimulation aimed at modifying spinal cord function. If included, participants will be randomly assigned to receive EAW with either active or sham tSS, performed 3 times per week for 36 weeks. Final testing of muscle function will be performed after 9 months.
Included participants
What’s involved
Type
Details
- Participants will be randomly assigned to receive exoskeleton-assisted walking (EAW) training combined with either active or sham transcutaneous spinal stimulation (tSS), performed 3 times per week for 36 weeks. - An exoskeleton is an externally worn powered robotic device to assist movement. - tSS is a non-invasive technique that uses surface electrodes to deliver electrical stimulation aimed at modifying spinal cord function. - Final testing of muscle function will be performed after 9 months.
Potential benefits
Main benefits
Standing/walking/mobility
Additional benefits
Bone health
General health
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Recruiting soon
- Trial start date
- 1 Jul 2026
- Organisation
- VA Office of Research and Development
- Trial recruitment status
- Recruiting soon
- Trial start date
- 1 Jul 2026
- Organisation
- VA Office of Research and Development
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more