Upper Limb Rehabilitation Using Non-invasive Spinal Cord Stimulation

Technology
Arm/hand function
Online since 21 April 2026, updated 5 days ago

About this trial

This trial is enrolling 40 participants with acute cervical spinal cord injury to test the effect of activity-based therapy (ABT) combined with transcutaneous spinal stimulation (tSS) on arm and hand function. ABT includes repetitive, intensive strength training and functional exercises. tSS is a non-invasive technique that uses surface electrodes to deliver electrical stimulation aimed at modifying spinal cord function. If included, participants will be randomly selected to receive activity-based upper-limb training with either active tSS or with sham stimulation, and will complete 20 therapist-guided training sessions over 6–8 weeks. Final testing of arm and hand function will be performed after 12 weeks.

Included participants

Gender
All
Age
≥ 16 years
Injury level
C1 - T1
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≤ 6 months
    Healthy volunteers
    No
    C1-T1
    Additionally, participants must
    NOT have a pacemaker

    What’s involved

    Type

    Technology

    Details

    - Participants will be randomly allocated to receive activity-based upper-limb training with either active transcutaneous spinal stimulation (tSS) or with sham stimulation and will complete 20 therapist-guided training sessions over 6–8 weeks. Each session will last around 45 minutes. - tSS is a non-invasive technique that uses surface electrodes to deliver electrical stimulation aimed at modifying spinal cord function. - Final testing of arm and hand function will be performed after 12 weeks.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Sensory function

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Apr 2026
    • Organisation
    • Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Apr 2026
    • Organisation
    • Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more