High-frequency Alternating Current Stimulation for Neurophatic Pain in Spinal Cord Injury

Technology
Pain
Online since 1 April 2026, updated 9 days ago

About this trial

This trial is enrolling 30 participants with thoracic or lower spinal cord injury to test the effect of high frequency transcutaneous spinal stimulation (tSS) on pain. tSS is a non-invasive technique that uses surface electrodes to deliver electrical stimulation aimed at modifying spinal cord function. If included, participants will be randomly assigned to receive either active high-frequency tSS (40 kHz) or sham stimulation in addition to standard treatment. Final assessment of pain will be performed after 15 days.

Included participants

Gender
All
Age
≥ 18 years
Injury level
T1 - S5
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≥ 3 months
    Healthy volunteers
    No
    T1-S5
    Additionally, participants must
    NOT have a cardiac pacemaker or any other implanted electrical device

    What’s involved

    Type

    Technology

    Details

    - Participants will be randomly assigned to receive either active high-frequency transcutaneous spinal stimulation (tSS) or sham stimulation in addition to standard treatment. Alternating current stimulation with a 40kHz frequency will be administered during 20-minute treatment sessions. - tSS is a non-invasive technique that uses surface electrodes to deliver electrical stimulation aimed at modifying spinal cord function. - Final assessment of pain will be performed after 15 days.

    Potential benefits

    Main benefits

    Pain

    Additional benefits

    General health

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 30 Jan 2026
    • Organisation
    • University of Castilla-La Mancha
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 30 Jan 2026
    • Organisation
    • University of Castilla-La Mancha

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more