The Effect of Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation on Bone Strength.

Rehabilitation
Standing/walking/mobility
Online since 26 April 2026, updated today

About this trial

This trial is enrolling 24 participants with chronic spinal cord injury to test the effect of exoskeleton-assisted walking combined with transcutaneous spinal stimulation (tSS) on lower limb function. tSS is a non-invasive technique that uses surface electrodes to deliver electrical stimulation aimed at modifying spinal cord function. If included, participants will be randomly assigned to receive overground exoskeleton-assisted walking training with either active tSS or sham stimulation. Final testing of lower limb function and bone health will be performed after 9 months.

Included participants

Gender
All
Age
21 - 60 years
Injury level
C5 - T10
  • Severity (AIS)?
  • AIS-C
    AIS-D
    Time since injury
    ≥ 3 years
    Healthy volunteers
    No
    C5-T10
    Additionally, participants must
    NOT have a baclofen pump or metal implants

    What’s involved

    Type

    Rehabilitation

    Details

    - Participants will be randomly assigned to receive overground exoskeleton-assisted walking training with either active transcutaneous spinal stimulation (tSS) or sham stimulation during 60-minute sessions performed 3 times per week over approximately 36 weeks. - tSS is a non-invasive technique that uses surface electrodes to deliver electrical stimulation aimed at modifying spinal cord function. - Final testing of lower limb function will be performed after 9 months.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    Bone health

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Jul 2026
    • Organisation
    • Bronx VA Medical Center
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Jul 2026
    • Organisation
    • Bronx VA Medical Center

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more