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Epidural Spinal Cord Stimulation for Restoring Walking in Spinal Cord Injury

Technology
Standing/walking/mobility
Online since 1 April 2026, updated 9 days ago
Curated trial

About this trial

This trial is enrolling 12 participants with chronic incomplete spinal cord injury to test the effect of epidural electrical stimulation (EES) combined with rehabilitation training on walking function. EES is an invasive technique that uses an implanted electrode placed next to the spinal cord to deliver electrical stimulation aimed at modifying spinal cord function. If included, participants will undergo surgical implantation of a stimulation device followed by individualized stimulation and rehabilitation therapy. Final testing for safety and walking function will be performed after 13 months.

Included participants

Gender
All
Age
16 - 65 years
Injury level
C1 - T9
  • Severity (AIS)?
    • AIS-C
    AIS-D
    Time since injury
    6 months - 3 years
  • Injury type

    • Traumatic

    Healthy volunteers
    No
    C1-T9
    Additionally, participants must
    NOT have an implanted cardiac pacemakers, cardioverters, or defibrillators

    What’s involved

    Type

    Technology

    Details

    - Participants will undergo surgical implantation of an epidural stimulation device followed by individualized epidural electrical stimulation (EES) and rehabilitation therapy. - EES is an invasive technique that uses an implanted electrode placed next to the spinal cord to deliver electrical stimulation aimed at modifying spinal cord function. - Final testing of walking function will be performed after 13 months.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    Arm/hand function

    Bladder health/function

    Bowel health

    General health

    Pain

    Sensory function

    Skin health

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 12 Dec 2025
    • Organisation
    • Second Affiliated Hospital, School of Medicine, Zhejiang University
    View on clinicaltrials.gov
    for more details
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 12 Dec 2025
    • Organisation
    • Second Affiliated Hospital, School of Medicine, Zhejiang University
    View on clinicaltrials.gov
    for more details

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

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