Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities

About this trial

This trial is enrolling 50 participants with spinal cord injury and other neurological conditions to compare the effect of cryoneurolysis with botulinum toxin (botox) on spasticity related pain. Cryoneurolysis is a minimally invasive technique that involves controlled freezing of peripheral nerves to temporarily disrupt nerve conduction and reduce muscle overactivity. Botox is a commonly used nerve blocker. If included, participants will be randomly assigned to receive either standard care with botox injections or cryoneurolysis. Participants in the botox group will have the option to receive cryoneurolysis after the 12-week assessment. Final testing of pain will be performed after 24 weeks.