Duraplasty for Acute Traumatic Spinal Cord Injury
About this trial
This trial is enrolling 66 participants with very acute spinal cord injury during their initial acute hospital stay after spinal cord injury to compare the effect of expansile duraplasty with standard surgery alone. Expansile duraplasty is a surgical procedure in which the dura, the outermost membrane protecting the spinal cord, is opened and expanded with a patch to create more space for injured spinal cord swelling. If included, participants will be randomly assigned to receive standard spinal cord surgery either with or without duraplasty. Final testing of neurological function will be performed after 6 months.
Included participants
Traumatic
What’s involved
Type
Details
- Participants will be randomly assigned to receive standard spinal cord surgery either with or without duraplasty. - Expansile duraplasty is a surgical procedure in which the dura of the spinal cord is opened and expanded with a dural patch to create more space for the injured spinal cord. - Final testing of neurological function will be performed after 6 months.
Potential benefits
Main benefits
General health
Additional benefits
Arm/hand function
Bladder health/function
Bowel health
Mental health and psychosocial factors
Pain
Sensory function
Standing/walking/mobility
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Recruiting soon
- Trial start date
- 1 Mar 2026
- Organisation
- University of California, San Francisco
- Trial recruitment status
- Recruiting soon
- Trial start date
- 1 Mar 2026
- Organisation
- University of California, San Francisco
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more