Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia

About this trial

This feasibility trial is enrolling 3 participants with chronic, cervical spinal cord injury previously enrolled in a hand and arm sensation study (NCT03898804) to test the effect of two types of nerve stimulation on hand and arm sensation. Participants will undergo intracortical microstimulation (ICMS), peripheral nerve stimulation (PNS), and combined ICMS + PNS. ICMS involves sending small electrical pulses to the part of the brain that processes sensation. PNS involves sending small electrical pulses to the nerves in the arm that transmit sensations from the hand. If included, participants will receive ICMS and PNS, and will perform functional tasks in virtual reality (VR). VR is a computer generated experience of visual displays that are similar to the real world, delivered through head-mounted displays such as smart-glasses. Final testing of arm and hand function will be performed after 2 years.