Long-term Follow-up for Epidural Stimulation in SCI

Technology
Standing/walking/mobility
Online since 16 October 2025, updated 19 days ago

About this trial

This trial is enrolling 91 participants with spinal cord injury who previously received an epidural stimulator to test the long-term effect of epidural spinal stimulation (eSS). eSS is an invasive technique that uses an implanted electrode placed next to the spinal cord to deliver electrical stimulation aimed at modifying spinal cord function. If included, participants will use previously established stimulation programs at home for activities such as standing or walking. Final testing will be performed after 1 year (and annually until the device is removed, turned off, or commercially approved).

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - S5
  • Severity (AIS)?
  • Time since injury
    All
    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    have received a neurostimulator and electrode array as part of a previous study

    What’s involved

    Type

    Technology

    Details

    - Participants will use previously established stimulation programs at home for activities such as standing or walking to test the long-term effect of epidural spinal stimulation (eSS). - eSS is an invasive technique that uses an implanted electrode placed next to the spinal cord to deliver electrical stimulation aimed at modifying spinal cord function. - Final testing will be performed after 1 year (and annually until the device is removed, turned off, or commercially approved).

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    Arm/hand function

    Bladder health/function

    Bowel health

    General health

    Mental health and psychosocial factors

    Sexual health

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • By invitation
    • Trial start date
    • 13 Jan 2025
    • Organisation
    • Kessler Foundation
    • Trial recruitment status
    • By invitation
    • Trial start date
    • 13 Jan 2025
    • Organisation
    • Kessler Foundation

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more