Virtual Reality Dual Task Training in SCI: Effects on Cognition and Cortical Activation

Rehabilitation
General health
Online since 4 September 2025, updated 98 days ago

About this trial

This trial is enrolling 45 participants with spinal cord injury to test the effect of virtual reality (VR)-based dual-task training (includes cognitive and motor tasks) with and without motor imagery. VR is a computer generated experience of visual displays that simulate the real world by way of head-mounted displays such as smart-glasses. Motor imagery refers to mentally visualizing oneself performing a movement without physically executing it, which can activate brain regions involved in the actual movement. If included, participants will be randomly assigned to one of three groups: (1) VR-based dual-task training with motor imagery (e.g., while visualizing themselves standing and walking); (2) VR-based dual-task training without motor imagery; or (3) a control group receiving only upper extremity strengthening. All groups will complete 12 sessions over 6 weeks. Final testing will be performed after 6 weeks.

Included participants

Gender
All
Age
18 - 60 years
Injury level
T1 - S5
  • Severity (AIS)?
  • Time since injury
    ≥ 3 months
    Healthy volunteers
    No
    T1-S5
    Additionally, participants must
    Have active shoulder flexion and abduction of at least 90 degrees
    Be able to sit in a chair for at least 30 minutes
    NOT have musculoskeletal pain >5 out of 10 on the Visual Analog Scale

    What’s involved

    Type

    Rehabilitation

    Details

    - Participants will be randomly assigned to one of three groups: (1) virtual reality (VR)-based dual-task training with motor imagery (i.e., while visualizing themselves standing and walking), (2) VR-based dual-task training without motor imagery, or (3) a control group receiving only upper extremity strengthening. - VR is a computer generated experience of visual displays that are similar to the real world, through head-mounted displays such as smart-glasses. - Motor imagery refers to mentally visualizing oneself performing a movement without physically executing it, which can activate similar brain regions involved in actual movement. - All groups will complete 12 sessions over 6 weeks. - Final testing will be performed after 6 weeks.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Mental health and psychosocial factors

    Pain

    Sensory function

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 16 Jun 2025
    • Organisation
    • Istinye University
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 16 Jun 2025
    • Organisation
    • Istinye University

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more