Exoskeleton Training on Balance Control and Turning in Ambulation in Individuals With Incomplete Spinal Cord Injury

Rehabilitation
Standing/walking/mobility
Online since 4 September 2025, updated 98 days ago

About this trial

This trial is enrolling 32 individuals with chronic incomplete spinal cord injury to test the effect of exoskeleton-assisted walking training on balance and mobility. The study investigates the ability to turn while walking, which requires coordinated movements of the head, trunk, pelvis, and limbs. If included, participants will be randomly assigned to one of three groups: (1) exoskeleton training using the EksoNR device; (2) conventional walking training; or (3) standard care without mobility intervention. Training sessions in the intervention groups are delivered twice weekly for 12 weeks. Four participants in the exoskeleton training group will undergo additional measurements of brain hemoglobin concentration using a non-invasive, optical technique (near-infrared spectroscopy [fNIRS]). All participants will be offered EksoNR training after the study concludes. Final testing of balance control and mobility will be performed after 4 months.

Included participants

Gender
All
Age
18 - 65 years
Injury level
C1 - L2
  • Severity (AIS)?
  • AIS-C
    AIS-D
    Time since injury
    ≥ 6 months
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    Yes
    C1-L2
    Additionally, participants must
    be able to walk independently at least 2 meters.
    be between 5'0" and 6'4" tall

    What’s involved

    Type

    Rehabilitation

    Details

    - Participants will be randomly assigned to one of three groups: (1) exoskeleton training using the EksoNR device, (2) conventional walking training, or (3) standard care without new mobility interventions. - Training sessions in the intervention groups are delivered twice weekly for 12 weeks. - All participants will be offered EksoNR training after the study concludes. - Final testing of balance control and mobility will be performed after 4 months.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    Arm/hand function

    General health

    Mental health and psychosocial factors

    Sensory function

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • Active
    • Trial start date
    • 1 Jun 2024
    • Organisation
    • Hong Kong Metropolitan University
    • Trial recruitment status
    • Active
    • Trial start date
    • 1 Jun 2024
    • Organisation
    • Hong Kong Metropolitan University

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more