Interest of a Musical Intervention on Stress Induced During Botulinum Toxin Injections in Spasticity (MUSIBOT)

Psychosocial/other
Mental health and psychosocial factors
Online since 4 September 2025, updated 62 days ago

About this trial

This trial is enrolling 80 participants with spinal cord injury or other central neurological damage, who receive regular botulinum toxin (Botox) injections, to test the effect of a personalized music intervention on injection-induced stress. Botox injections are a painful treatment frequently used to reduce spasticity following central neurological damage. If included, participants will be randomly assigned to receive Botox injections either with or without music before their first session, followed by a second session with music for all participants. Final testing of stress will be performed after 4 months.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - S5
  • Severity (AIS)?
  • Time since injury
    All
    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    Be enrolled in a French Social Security system

    What’s involved

    Type

    Psychosocial/other

    Details

    - Participants will be randomly assigned to receive botulinum toxin (Botox) injections either with or without music before their first session, followed by a second session with music for all participants. - Botox injections are a painful treatment frequently used to treat spasticity following central neurological damage. - Final testing of injection-induced stress will be performed after 4 months.

    Potential benefits

    Main benefits

    Mental health and psychosocial factors

    Additional benefits

    General health

    Pain

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 25 Apr 2025
    • Organisation
    • University Hospital, Clermont-Ferrand
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 25 Apr 2025
    • Organisation
    • University Hospital, Clermont-Ferrand

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more