The Effects of Eccentric Compared to Standard Strength Training in Primary Spinal Cord Injury Rehabilitation

Rehabilitation
Arm/hand function
Online since 26 November 2025, updated 15 days ago

About this trial

This trial is enrolling 20 participants with spinal cord injury undergoing primary rehabilitation to test the effect of eccentric arm-crank training on arm and hand function. Eccentric training involves lengthening muscles under tension, for example a controlled lowering of your arm after a biceps curl until it is straight. If included, participants will be randomly assigned to undergo 20 training sessions using either the KREHA arm-crank device or standard strength training, over 12 weeks. Final testing of arm and hand strength will be performed after 12 weeks.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - S5
  • Severity (AIS)?
  • Time since injury
    All
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    participate in the routine strength training program during primary SCI rehabilitation at the study center

    What’s involved

    Type

    Rehabilitation

    Details

    - Participants will be randomly assigned to undergo 20 training sessions using either the KREHA arm-crank device or standard strength training equipment over 12 weeks. - Final testing of arm and hand will be performed after 12 weeks.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    Bladder health/function

    Bowel health

    General health

    Mental health and psychosocial factors

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Mar 2026
    • Organisation
    • Swiss Paraplegic Research, Nottwil
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Mar 2026
    • Organisation
    • Swiss Paraplegic Research, Nottwil

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more