The Effect of Probiotic and Prebiotic Supplementation on Gastrointestinal Health in Individuals With Chronic Spinal Cord Injury
About this trial
This trial is enrolling 50 participants with chronic spinal cord injury to test the effect of probiotic and prebiotic supplementation on bowel health. If included, participants will be randomly assigned to first take either a probiotic supplement daily for 8 weeks, followed by a 4-week wash-out period and then a prebiotic supplement for another 8 weeks, or vice versa. Probiotic supplements contain live bacteria that may influence the balance of microorganisms in the gut. Prebiotic supplements are a type of fiber that can serve as a food source for certain gut bacteria and may play a role in digestive processes. Final testing of bowel health will be performed after 20 weeks.
Included participants
What’s involved
Type
Details
- Participants will be randomly assigned to first take either a probiotic supplement daily for 8 weeks, followed by a 4-week wash-out period and then a prebiotic supplement for another 8 weeks, or vice versa. - Probiotic supplements contain live bacteria that may influence the balance of microorganisms in the gut. - Prebiotic supplements are a type of fiber that can serve as a food source for certain gut bacteria and may play a role in digestive processes. - Final testing of bowel health will be performed after 20 weeks.
Potential benefits
Main benefits
Bowel health
Additional benefits
General health
Mental health and psychosocial factors
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Recruiting
- Trial start date
- 11 Aug 2025
- Organisation
- Swiss Paraplegic Research, Nottwil
- Trial recruitment status
- Recruiting
- Trial start date
- 11 Aug 2025
- Organisation
- Swiss Paraplegic Research, Nottwil
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more