At-Home Genital Nerve Stimulation for SCI Bowel

Technology
Bowel health
Online since 4 September 2025, updated 62 days ago

About this trial

This pilot trial is enrolling 12 participants with chronic cervical or thoracic spinal cord injury to test the effect of genital nerve stimulation (GNS) in the pelvic area (near the genitals) on bowel health. GNS is a non-invasive technique that uses electrodes on the skin to deliver electrical stimulation aimed at modifying spinal cord function. If included, participants will receive either GNS or sham GNS for 6–8 hours daily for 4 weeks, at home. Final testing of bowel health will be performed after 6 weeks.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - T12
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≥ 6 months
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C1-T12
    Additionally, participants must
    NOT have a cardiac pacemaker, implanted defibrillator, or other implanted functional electrical stimulation device if, upon clinical evaluation, it may have an interaction with the stimulation

    What’s involved

    Type

    Technology

    Details

    - Participants will receive genital nerve stimulation (GNS) in the pelvic area (near the genitals) for 6–8 hours daily for 4 weeks at home. - GNS is a non-invasive technique that uses electrodes on the skin to deliver electrical stimulation aimed at stimulating the genital nerves to modify spinal cord function. - In men, two electrodes will be placed 2 cm apart on the penis. In women, electrodes will be placed near the clitoris and on the outer vaginal area or upper inner thigh. - Final testing of bowel health will be performed after 6 weeks.

    Potential benefits

    Main benefits

    Bowel health

    Additional benefits

    General health

    Mental health and psychosocial factors

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Mar 2025
    • Organisation
    • MetroHealth Medical Center
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Mar 2025
    • Organisation
    • MetroHealth Medical Center

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more