Early BOTOX After Spinal Cord Injury

Drug
Bladder health/function
Online since 1 April 2026, updated 9 days ago

About this trial

This trial is enrolling 10 individuals with acute spinal cord injury to test the safety and feasibility of botulinum toxin (Botox) to modulate bladder activity. If included, participants will be randomly assigned to receive either a 200-unit Botox injection or a placebo (saline) injection into the bladder. Final testing of safety and feasibility will be performed after 1 year.

Included participants

Gender
All
Age
18 - 65 years
Injury level
C1 - T6
  • Severity (AIS)?
  • AIS-A
    AIS-B
    Time since injury
    ≤ 20 weeks
    Healthy volunteers
    No
    C1-T6

    What’s involved

    Type

    Drug

    Details

    - Participants will be randomly assigned to receive either a 200-unit Botox injection or a placebo (saline) injection into the bladder. - Final testing of safety and feasibility will be performed after 1 year.

    Potential benefits

    Main benefits

    Bladder health/function

    Additional benefits

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • By invitation
    • Trial start date
    • 27 Jul 2024
    • Organisation
    • University of Washington
    • Trial recruitment status
    • By invitation
    • Trial start date
    • 27 Jul 2024
    • Organisation
    • University of Washington

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more