Comparing Upper Limb Surgery and Botulinum Toxin for Spasticity: A Paired Design Study

Surgery
Spasticity
Online since 11 April 2025, updated 5 days ago

About this trial

This trial is enrolling 30 participants with cervical spinal cord injury, traumatic brain injury, or stroke to test the effect of upper limb surgery versus botulinum toxin (botox) injections on spasticity. If included, participants will first receive botox injections, followed by tendon lengthening surgery at least 3 months later. Final testing of spasticity will be performed after 6 months.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - T1
  • Severity (AIS)?
  • Time since injury
    ≥ 6 months
    Healthy volunteers
    No
    C1-T1

    What’s involved

    Type

    Surgery

    Details

    - Participants will first receive botulinum toxin (botox) injections, followed by tendon lengthening surgery at least 3 months later. - Final testing of spasticity will be performed after 6 months.

    Potential benefits

    Main benefits

    Spasticity

    Additional benefits

    Arm/hand function

    General health

    Mental health and psychosocial factors

    Pain

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 7 Jan 2025
    • Organisation
    • Vastra Gotaland Region
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 7 Jan 2025
    • Organisation
    • Vastra Gotaland Region

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more