The Outcome of Injured Cervical Spinal Cord with Uncontrolled Swelling Under Duraplasty

Surgery
General health
Online since 14 March 2025, updated 235 days ago

About this trial

This trial is enrolling 104 participants with acute cervical spinal cord injury to test the effect of duraplasty alongside bony decompression on movement and sensation. Duraplasty is a procedure where the protective covering (dura) around the spinal cord is carefully opened and enlarged to reduce pressure. Bony decompression is a surgery where part of the bone around the spinal cord is removed to create more space, also to relieve pressure. If included, participants will undergo decompression surgery either with or without duraplasty. Final testing of movement and sensory function will be performed after 1 year.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C2 - T1
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    Time since injury
    ≤ 72 null
  • Injury type
  • Traumatic

    Healthy volunteers
    Yes
    C2-T1
    Additionally, participants must
    NOT have thoracic or lumbar traumatic spinal cord injury

    What’s involved

    Type

    Surgery

    Details

    - Participants will undergo bony decompression either with or without duraplasty. - Bony decompression is a surgery where part of the bone around the spinal cord is removed to create more space and relieve pressure. - Duraplasty is a procedure where the protective covering around the spinal cord (i.e. dura) is carefully opened and enlarged to further reduce pressure. - Final testing of movement and sensory function will be performed after 1 year.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Bladder health/function

    Bowel health

    Mental health and psychosocial factors

    Pain

    Sensory function

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Mar 2025
    • Organisation
    • Chang Gung Memorial Hospital
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Mar 2025
    • Organisation
    • Chang Gung Memorial Hospital

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more