Muscle-tendon Interaction in the Spastic Sural Triceps During Gait

General health
Online since 25 October 2024, updated 172 days ago

About this trial

This project aims to study the mechanical behavior of the muscle-tendon unit (MTU) of the gastrocnemius medialis (GM) and the Achilles tendon (AT) in post-stroke and spinal cord injured (SCI) patients...

Included participants

Gender
All
Age
≥ 18 years
Injury level
C2 - L5
  • Severity (AIS)?
  • AIS-C
    AIS-D
    Time since injury
    All
    Healthy volunteers
    Yes
    C2-L5

    What’s involved

    Type

    Observational

    Details

    Primary Objective: Evaluate the respective contributions of the gastrocnemius medialis (GM) muscle and the Achilles tendon (AT) within the muscle-tendon unit (MTU) during the single support phase of walking in post-stroke patients compared to healthy subjects. Study Description: Strokes often lead to spastic paresis, degrading patients' walking performance. Instrumented gait analysis allows for the evaluation of these performances to propose adapted therapeutic strategies. This project will compare muscle and tendon behavior during walking between healthy individuals and post-stroke patients. Methodology: * Participants: Adult post-stroke patients or incomplete SCI patients with voluntary motor function on the triceps surae and walking capacity. Control group composed of healthy adults. * Procedures: * Measure the force/length profile of the GM on an isokinetic dynamometer with simultaneous ultrasound. * Conduct gait analysis coupled with ultrasound to measure the lengths of the AT and GM. * Compare muscle and tendon length data during the stance phase of the gait cycle between the two groups.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 15 Nov 2024
    • Organisation
    • Nantes University Hospital
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 15 Nov 2024
    • Organisation
    • Nantes University Hospital

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more