Epidural Electrical Stimulation for Spinal Cord Injury Patients and Corticospinal Motor Circuit Improvement

Surgery
Mechanism of action
Online since 3 July 2024, updated 219 days ago

About this trial

The study aims to examine the plausible interventional mechanisms underlying the effects of epidural spinal cord stimulation....

Included participants

Gender
All
Age
20 - 70 years
Injury level
C1 - S5
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≥ 1 year
    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    NOT have an active cancer diagnosis

    What’s involved

    Type

    Surgery

    Details

    The purpose of this study is for the treatment of spinal cord injury (SCI) paralysis patients use the signal by electrophysiological analysis of epidural spinal cord stimulation (SCS) settings that promote limbs activity so that SCI patients can restore motor ability under multiple sensory stimuli and multimodal electrical stimulation rehabilitation. The investigators hope to establish an atresia nerve regulation strategy and observe that the original blocked neural circuits can improve nerve plasticity by SCS. Even can establish new connections through residual nerves and allow SCI patients to rebuild neural circuits without SCS to restore limbs mobility and improve quality of life.

    Potential benefits

    Main benefits

    Mechanism of action

    Additional benefits

    Arm/hand function

    Bladder health/function

    Bowel health

    General health

    Mental health and psychosocial factors

    Spasticity

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 30 Apr 2024
    • Organisation
    • Buddhist Tzu Chi General Hospital
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 30 Apr 2024
    • Organisation
    • Buddhist Tzu Chi General Hospital

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more