Spinal Cord Stimulation for Lower Extremity Function

Technology
Standing/walking/mobility
Online since 8 October 2024, updated 73 days ago

About this trial

This trial is enrolling 10 participants with chronic incomplete spinal cord injury to test the safety of epidural spinal cord stimulation (SCS) and its effect on lower extremity function. SCS is a technique for stimulating the spinal cord with an implanted electrode placed next to the spinal cord to modify spinal cord function. Investigators want to see if spine imaging can be utilized as a marker to predict which patients will respond to SCS. If included, participants will receive an SCS implant and undergo tailored rehabilitation (4x weekly for 5 months). Final testing of safety and lower extremity function will be performed after 6 months.

Included participants

Gender
All
Age
18 - 65 years
Injury level
C6 - T10
  • Severity (AIS)?
  • AIS-B
    AIS-C
    Time since injury
    ≥ 12 months
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C6-T10

    What’s involved

    Type

    Technology

    Details

    - Participants will receive an SCS implant and undergo tailored rehabilitation (4x weekly, for 5 months). - SCS is a technique for stimulating the spinal cord with an implanted electrode placed next to the spinal cord to modify spinal cord function. - Final testing of safety and lower extremity function will be performed after 6 months.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    Arm/hand function

    General health

    Sensory function

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Jul 2024
    • Organisation
    • Brigham and Women's Hospital
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Jul 2024
    • Organisation
    • Brigham and Women's Hospital

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more