Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury

Drug
General health
Online since 5 October 2024, updated 60 days ago

About this trial

This phase I trial is enrolling 36 participants with chronic spinal cord injury to assess the safety, tolerability, and effect of a drug - EC5026 - on neuropathic pain. If included, participants will be randomly assigned to receive the drug or a placebo once daily for 14 consecutive days. Final testing of safety, tolerability, and changes in pain will be performed after 30 days.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C2 - T12
  • Severity (AIS)?
  • Time since injury
    ≥ 12 months
    Healthy volunteers
    No
    C2-T12
    Additionally, participants must
    NOT have other chronic neuropathic pain conditions, including painful diabetic neuropathy, HIV-associated neuropathic pain, chemotherapy or ethanol-associated neuropathy.
    be United States veterans

    What’s involved

    Type

    Drug

    Details

    - Participants will receive a drug (EC5026) or a placebo once daily for 14 consecutive days. - Final testing of safety and tolerability will be performed after 30 days.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Pain

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Dec 2024
    • Organisation
    • EicOsis Human Health Inc.
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Dec 2024
    • Organisation
    • EicOsis Human Health Inc.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more