Epidural Stimulation for Upper Extremity Function

Technology
Arm/hand function
Online since 15 October 2024, updated 23 days ago

About this trial

This trial is enrolling 20 participants with cervical spinal cord injury who have undergone nerve transfer surgery at least 6 months ago, to test the effect of epidural spinal cord stimulation (SCS) on hand and arm function. SCS is a technique for stimulating the spinal cord; in this case, temporary SCS leads will be imlanted under the skin in the cervical spine region above the injury area. If included, participants will receive SCS for 4 weeks. Final testing of hand and arm function will be performed after 6 weeks.

Included participants

Gender
All
Age
18 - 65 years
Injury level
C1 - T1
  • Severity (AIS)?
  • Time since injury
    All
    Healthy volunteers
    No
    C1-T1
    Additionally, participants must
    NOT have a functional implanted device (pacemaker, vagus nerve device, baclofen pump)
    have had upper extremity nerve transfer > 6 months prior to enrollment

    What’s involved

    Type

    Technology

    Details

    - Participants will receive epidural spinal cord stimulation (SCS) for 4 weeks. - SCS is a technique for stimulating the spinal cord to modify spinal cord function. This study uses percutaneous leads which are inserted in the cervical region of the spine. - Final testing of hand and arm function will be performed after 6 weeks.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Pain

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Sep 2024
    • Organisation
    • Brigham and Women's Hospital
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Sep 2024
    • Organisation
    • Brigham and Women's Hospital

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more