The Therapeutic Effect of Thalidomide in Syringomyelia

Drug
General health
Online since 27 June 2024, updated 360 days ago

About this trial

This trial is enrolling 30 participants with refractory syringomyelia to test the effect of thalidomide. Thalidomide is a drug with anti-inflammatory and immune modifying properties. If included, participants will receive 50–200 mg of thalidomide once at nightime. Final testing of sensory and motor scores will be performed after 3 months.

Included participants

Gender
All
Age
18 - 80 years
Injury level
C1 - S5
  • Severity (AIS)?
  • Time since injury
    All
    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    NOT have a history of psychiatric diseases or seizures
    NOT have transplanted organs
    HAVE had surgical treatment of syringomyelia that was ineffective, or

    What’s involved

    Type

    Drug

    Details

    - Participants will receive 50 – 200 mg of thalidomide once at nightime. - Thalidomide is a drug with anti-inflammatory and immunomodulatory properties. - Final testing of sensory and motor scores will be performed after 3 months.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Pain

    Sensory function

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Feb 2024
    • Organisation
    • Xuanwu Hospital, Beijing
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Feb 2024
    • Organisation
    • Xuanwu Hospital, Beijing

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more