Influence of Spinal Stimulation Frequency on Spasticity, Motor Control, and Pain After Spinal Cord Injury

Technology
Spasticity
Online since 25 June 2024, updated 179 days ago

About this trial

This trial is enrolling 46 individuals with cervical/thoracic spinal cord injury occuring at least 3 months ago to test the effect of different frequencies of transcutaneous spinal stimulation (TSS) on spasticity, muscle strength, and pain. TSS is a technique for stimulating the spinal cord via skin-surface electrodes to modify spinal cord function. If included, participants will undergo TSS for 30 minutes at 3 different frequencies. Participants must come into the study center 4 consecutive days a week for 2-3 hours per day over 2-3 weeks. Final testing of spasticity, muscle strength and pain will be performed 20 minutes after testing.

Included participants

Gender
All
Age
≥ 16 years
Injury level
C1 - T12
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≥ 3 months
    Healthy volunteers
    No
    C1-T12
    Additionally, participants must
    NOT have had heart issues
    NOT have implanted stimulators

    What’s involved

    Type

    Technology

    Details

    - Participants will undergo TSS for 30 minutes at 3 different frequencies. - Participants will be required to come into the study center 4 consecutive days a week for 2-3 hours per day across 2-3 weeks. - Final testing of spasticity, muscle strength and pain will be performed 20 minutes after testing.

    Potential benefits

    Main benefits

    Spasticity

    Additional benefits

    General health

    Pain

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 19 Feb 2024
    • Organisation
    • Shepherd Center, Atlanta GA
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 19 Feb 2024
    • Organisation
    • Shepherd Center, Atlanta GA

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more