Reciprocal Inhibition Versus Reciprocal Facilitation In Spinal Cord Injury Patients

Online since 12 September 2023, updated 167 days ago

About this trial

Reciprocal inhibition is a medulla spinalis control mechanism that facilitates motor activities in healthy people. As the agonist muscle contracts, the antagonist muscle is inhibited so that the agoni...

Included participants

Gender
All
Age
25 - 60 years
Injury level
Level not specified
  • Severity (AIS)?
  • Time since injury
    All
    Healthy volunteers
    Yes
    Level not specified

    What’s involved

    Type

    Observational

    Details

    Reciprocal inhibition is a spinal segmental control mechanism that facilitates motor activities in healthy people and is also used in the treatment of spasticity. When we look at the literature, there are some studies claiming that this is reversed in patients with upper motor neuron lesions and that there is reciprocal facilitation instead of inhibition. However, the proposed evidence is not convincing. Our aim in this study was to investigate the presence of reciprocal facilitation in detail in patients with upper motor neuron lesions. In our study, which we conducted with five patients with spinal cord lesions and five healthy individuals, both the tibialis anterior and soleus muscles of the cases were recorded using surface and multi-motor unit electromyography (EMG) electrodes. To elicit an H reflex in the soleus muscle, an electric current was delivered through the popliteal fossa using the monopolar technique. We tapped the Achilles tendon with the reflex hammer to elicit a T reflex. Since the H-reflex and T-reflex responses were detected in the tibialis anterior muscle surface and multi-motor unit EMG recordings, the findings were evaluated as direct stimulation, cross-talk, and reciprocal facilitation. Methodologically, we aimed to be a guiding study for future studies.

    Potential benefits

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 5 Jan 2023
    • Organisation
    • Istanbul Physical Medicine Rehabilitation Training and Research Hospital
    • Trial recruitment status
    • Ended
    • Trial start date
    • 5 Jan 2023
    • Organisation
    • Istanbul Physical Medicine Rehabilitation Training and Research Hospital

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more